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Artificial intelligence for disparities in knee pain assessment

An algorithm developed through machine learning on existing radiological data from diverse people has the potential to improve the diagnosis and management of knee pain from osteoarthritis and reduce racial disparities in the assessment of knee pain.

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  1. Lawrence, R. C. et al. Arthritis Rheum. 41, 778–799 (1998).

    Article  CAS  Google Scholar 

  2. Altman, R. D., Hochberg, M. C., Moskowitz, R. W. & Schnitzer, T. J. Arthritis Rheum. 43, 1905–1915 (2000).

    Article  Google Scholar 

  3. Sharkness, C., Hamburger, S., Moore, R. & Kaczmarek, R. Public Health Rep. 106, 70–74 (1993).

    Google Scholar 

  4. Wilson, M. G., May, D. S. & Kelly, J. J. Ethn. Dis. 4, 57–67 (1994).

    CAS  PubMed  Google Scholar 

  5. Hoagland, F. T., Oishi, C. S. & Gialamas, G. G. Ann. Rheum. Dis. 54, 107–110 (1995).

    Article  Google Scholar 

  6. Pierson, E., Cutler, D., Leskovec, J., Mullainathan, S. & Obermeyer, Z. Nat. Med. (2020).

  7. Whittle, J., Conigliaro, J., Good, C. B. & Lofgren, R. P. N. Engl. J. Med. 329, 621–627 (1993).

    Article  CAS  Google Scholar 

  8. Hannan, E., Kilburn, H. J., O’Donnell, J. F., Lukacik, G. & Shields, E. P. Med. Care 29, 430–441 (1991).

    Article  CAS  Google Scholar 

  9. Bedson, J. & Croft, P. R. BMC Musculoskelet. Disord. 9, 116 (2008).

    Article  Google Scholar 

  10. Ibrahim, S. A., Siminoff, L. A., Burant, C. J. & Kwoh, C. K. Med. Care 40, I44–I51 (2002).

    Article  Google Scholar 

  11. Ibrahim, S. A., Siminoff, L. A., Burant, C. J. & Kwoh, C. K. Arthritis Rheum. 46, 2429–2435 (2002).

    Article  Google Scholar 

  12. Cai, X., Cram, P. & Vaughan-Sarrazin, M. Clin. Orthop. Relat. Res. 470, 1185–1193 (2012).

    Article  Google Scholar 

Download references


S.A.I. is supported in part by a K24 Mid-Career Development Award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (grant K24AR05529).

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Correspondence to Said A. Ibrahim.

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Ibrahim, S.A. Artificial intelligence for disparities in knee pain assessment. Nat Med 27, 22–23 (2021).

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