Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.


COVID-19-induced Kawasaki disease

Lancet 395, 1771–1778 (2020)

Cell (2020)

Children and young adults usually experience a mild form of COVID-19. However, in May, medical doctors in Bergamo, Italy, the city hardest hit by COVID-19, reported a cluster of children with features of the pediatric vascular inflammatory syndrome Kawasaki disease. The absolute number of cases was small — 10 children in a region that had, at that point, seen more than 130,000 cases of COVID-19 — but it represented a 30-fold increase in the local incidence of Kawasaki disease.

The authors noted that five of the ten patients had an acute form of the disease: Kawasaki disease shock syndrome. Affected children were also on average older than the normal age for the diagnosis of Kawasaki disease and showed more cardiovascular involvement. A rare but serious pediatric complication of COVID-19, multisystem inflammatory syndrome in children, has since been described.

Author information



Corresponding author

Correspondence to Thiago Carvalho.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Carvalho, T. COVID-19-induced Kawasaki disease. Nat Med 26, 1807 (2020).

Download citation


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing