Extended Data Fig. 4: Unchanged frequency of CMV-specific effector T cells detected by intracellular cytokine staining. | Nature Medicine

Extended Data Fig. 4: Unchanged frequency of CMV-specific effector T cells detected by intracellular cytokine staining.

From: Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity

Extended Data Fig. 4

PBMCs were stimulated with CMV pp65 peptide pools for 6h and cytokine production was evaluated by ICS in bNAb+ATI individuals at week -2 and week 12. (ab) Cytokine analysis of CD8+ (a) or CD4+ T cells (b) at week -2 and week 12 after CMV pp65 stimulation. Net frequency of stimulated condition was calculated by subtracting frequency detected in a DMSO control. Symbols represent biologically independent samples from n=9 bNAb+ATI individuals. Lines connect data from the same donor. Bars show median values. P values are indicated in graphs and were calculated by paired two-tailed Wilcoxon test.

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