Extended Data Fig. 3: Individual Gag-specific T cell responses measured by ICS. | Nature Medicine

Extended Data Fig. 3: Individual Gag-specific T cell responses measured by ICS.

From: Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity

Extended Data Fig. 3

(ab) Net frequency of total cytokine+ CD8+ (a) or CD4+ cells (b) after Gag stimulation for each individual study participant. Total cytokine+ cells include cells that express at least one cytokine/effector function upon Gag stimulation (CD107A, IFNγ, MIP1β and/or TNFα for CD8+; CD40L, IFNγ, IL-2 and/or TNFα for CD4+). Net value was calculated by subtracting frequency of total cytokine+ cells detected in a DMSO control. ND: Week 18 sample was not available for individual 9244. *9242 week 18 on ART after viral rebound at week 15.

Back to article page