Extended Data Fig. 6: Paired transcriptomic and proteomic analysis. | Nature Medicine

Extended Data Fig. 6: Paired transcriptomic and proteomic analysis.

From: iPSC modeling of young-onset Parkinson’s disease reveals a molecular signature of disease and novel therapeutic candidates

Extended Data Fig. 6

Pearson correlation plots of (a) transcriptomic and (b) proteomic data. (c) PCA plot of all detected proteins. (d) PCA plot of matching RNA-Seq transcripts. (e) PCA plot of matching proteins. (f) PCA plots of filtered data with 190iPD line omitted. (g) Matched GSEA terms conducted on 190iPD omitted data set n=9 CTR n=6 PD term significance determined by FDR <0.1.

Back to article page