Mass administration of azithromycin to young children at risk of dying could reduce harmful intestinal pathogenic bacteria and impact survival, but also increase antibiotic resistance.
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References
Doan. T. et al. Nat. Med. https://doi.org/10.1038/s41591-019-0533-0 (2019).
Porco, T. C. et al. J. Am. Med. Assoc. 302, 962–968 (2009).
Keenan, J. D. et al. N. Engl. J. Med. 378, 1583–1592 (2018).
Oldenburg, C. E. et al. Am. J. Trop. Med. Hyg. 100, 691–695 (2019).
Arzika, A. M. et al. PLoS Med. 16, e1002835 (2019).
Chandramohan, D. et al. N. Engl. J. Med. 380, 2197–2206 (2019).
Doan, T. et al. Open Forum Infect. Dis. 5, ofy182, https://doi.org/10.1093/ofid/ofy182 (2018).
Liu, J. et al. Lancet 388, 1291–1301 (2016).
Rogawski, E.T. et al. Lancet Glob. Health 6, e1319–e1328.
Whitty, C. J., Glasgow, K. W., Sadiq, S. T., Mabey, D. C. & Bailey, R. Pediatr. Infect. Dis. J. 18, 955–958 (1999).
Keenan, J. D. et al. PLoS Negl. Trop. Dis. 13, e0007442 (2019).
Doan, T. et al. N. Engl. J. Med. 380, 2271–2273 (2019).
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Bhutta, Z.A. The benefits and risks of mass antibiotic use for reducing child mortality. Nat Med 25, 1332–1334 (2019). https://doi.org/10.1038/s41591-019-0576-2
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DOI: https://doi.org/10.1038/s41591-019-0576-2