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ANTIMICROBIAL RESISTANCE

Machine-learning-assisted selection of antibiotic prescription

Machine learning can use patients’ demographic information and previous clinical history to help physicians select the antibiotics most likely to successfully treat urinary tract infections, despite growing levels of resistance.

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Fig. 1: A machine-learning approach to prescribing antibiotics for UTIs.

References

  1. Roope, L. S. J. et al. Science 364, eaau4679 (2019).

    Article  Google Scholar 

  2. Whittles, L. K., White, P. J. & Didelot, X. PLoS Med. 14, e1002416 (2017).

    Article  Google Scholar 

  3. Yelin, I. et al. Nat. Med. https://doi.org/10.1038/s41591-019-0503-6 (2019).

  4. Dolk, F. C. K., Pouwels, K. B., Smith, D. R. M., Robotham, J. V. & Smieszek, T. J. Antimicrob. Chemother. 73(Suppl. 2), ii2–ii10 (2018).

    Article  CAS  Google Scholar 

  5. Ahmed, H. et al. PLoS One 13, e0190521 (2018).

    Article  Google Scholar 

  6. Pouwels, K. B. et al. J. Antimicrob. Chemother. 73, 1700–1707 (2018).

    Article  CAS  Google Scholar 

  7. Flores-Mireles, A. L., Walker, J. N., Caparon, M. & Hultgren, S. J. Nat. Rev. Microbiol. 13, 269–284 (2015).

    Article  CAS  Google Scholar 

  8. Didelot, X., Walker, A. S., Peto, T. E., Crook, D. W. & Wilson, D. J. Nat. Rev. Microbiol. 14, 150–162 (2016).

    Article  CAS  Google Scholar 

  9. Holmes, A. H. et al. Lancet 387, 176–187 (2016).

    Article  CAS  Google Scholar 

  10. Oonsivilai, M. et al. Wellcome Open Res. 3, 131 (2018).

    Article  Google Scholar 

  11. McAdams, D., Wollein Waldetoft, K., Tedijanto, C., Lipsitch, M. & Brown, S. P. PLoS Biol. 17, e3000250 (2019).

    Article  CAS  Google Scholar 

  12. Andersson, D. I. & Hughes, D. Nat. Rev. Microbiol. 8, 260–271 (2010).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Xavier Didelot.

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Didelot, X., Pouwels, K.B. Machine-learning-assisted selection of antibiotic prescription. Nat Med 25, 1033–1034 (2019). https://doi.org/10.1038/s41591-019-0517-0

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