MICROBIOME

Bacteria to alleviate metabolic syndrome

Heat-inactivated Akkermansia muciniphila helps alleviate features of metabolic syndrome in overweight and obese subjects.

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Fig. 1: Mild heat inactivation of Akkermansia muciniphila improves metabolic benefits in obese and overweight human subjects.

References

  1. 1.

    Kootte, R. S. et al. Cell Metab. 26, 611–619 (2017).

    CAS  Article  Google Scholar 

  2. 2.

    Cani, P. D. & De Vos, W. M. Front. Microbiol. 8, 1–8 (2017).

    Article  Google Scholar 

  3. 3.

    Shin, N. R. et al. Gut 63, 727–735 (2014).

    CAS  Article  Google Scholar 

  4. 4.

    Anhê, F. F., Varin, T. V., Schertzer, J. D. & Marette, A. Can. J. Diabetes 41, 439–447 (2017).

    Article  Google Scholar 

  5. 5.

    Everard, A. et al. Proc. Natl Acad. Sci. USA 110, 9066–9071 (2013).

    CAS  Article  Google Scholar 

  6. 6.

    Plovier, H. et al. Nat. Med. 23, 107–113 (2017).

    CAS  Article  Google Scholar 

  7. 7.

    Cani, P. D. et al. Diabetes 56, 1761–1772 (2007).

    CAS  Article  Google Scholar 

  8. 8.

    Depommier, C. et al. Nat. Med. https://doi.org/10.1038/s41591-019-0495-2 (2019).

  9. 9.

    Sakai, T. et al. J. Nutr. Sci. Vitaminol. (Tokyo) 59, 144–147 (2013).

    CAS  Article  Google Scholar 

  10. 10.

    Gu, Y. et al. Diabetes Res. Clin. Pract. 141, 140–147 (2018).

    Article  Google Scholar 

  11. 11.

    McPhee, J. B. & Schertzer, J. D. Clin. Sci. 129, 1083–1096 (2015).

    CAS  Article  Google Scholar 

  12. 12.

    Cavallari, J. F. et al. Cell Metab. 25, 1063–1074.e3 (2017).

    CAS  Article  Google Scholar 

Download references

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Correspondence to André Marette.

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Anhê, F.F., Schertzer, J.D. & Marette, A. Bacteria to alleviate metabolic syndrome. Nat Med 25, 1031–1033 (2019). https://doi.org/10.1038/s41591-019-0516-1

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