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The future of individualized health maintenance

Multi-omics longitudinal profiling of individuals can detect subtle changes in health status at the earliest possible time point, allowing preemptive initiation of mechanism-appropriate disease-prevention strategies.

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  1. Schüssler-Fiorenza Rose, S. M. Nat . Med. (2019).

  2. Shilaih, M., Clerck, V., Falco, L., Kubler, F. & Leeners, B. Sci. Rep. 7, 1294 (2017).

    Article  Google Scholar 

  3. Huffaker, M. F., Carchia, M. & Harris, B. U. et al. Am. J. Respir. Crit. Care Med. 198, 320–328 (2018).

    Article  Google Scholar 

  4. Zeevi, D., Korem, T. & Zmora, N. et al. Cell 163, 1079–1094 (2015).

    Article  CAS  Google Scholar 

  5. Catala, A., Culp-Hill, R., Nemkov, T. & D’Alessandro, A. Metabolomics 14, 100 (2018).

    Article  Google Scholar 

  6. Li, L., Cheng, W. Y. & Glicksberg, B. S. et al. Sci. Transl. Med. 7, 311ra174 (2015).

    Article  Google Scholar 

  7. Hall, H., Perelman, D. & Breschi, A. et al. PLoS Biol. 16, e2005143 (2018).

    Article  Google Scholar 

  8. Parikh, R. B., Schwartz, J. S. & Navathe, A. S. New Engl. J. Med. 376, 1609–1612 (2017).

    Article  Google Scholar 

  9. Hollands, G. J., French, D. P. & Griffin, S. J. et al. BMJ (Clin. Res. Ed.) 352, i1102 (2016).

    Google Scholar 

  10. Turnwald, B. P., Goyer, J. P., Boles, D. Z., Silder, A., Delp, S. L. & Crum, A. J. Nat. Hum. Behav. 3, 48 (2019).

    Article  Google Scholar 

  11. Gigerenzer, G. & Garcia-Retamero, R. Psychol. Rev. 124, 179–196 (2017).

    Article  Google Scholar 

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Correspondence to Steven R. Steinhubl.

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S.R.S. is supported by the National Institutes of Health grants UL1TR001114 and U24OD023176 and a grant from the Qualcomm Foundation.

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Steinhubl, S.R. The future of individualized health maintenance. Nat Med 25, 712–714 (2019).

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