Vaccination with the tuberculosis (TB) vaccine Bacillus Calmette–Guérin (BCG) into the lungs of Rhesus macaques induces specific, local immune responses that delay infection in some animals and completely prevent it in others while protecting against TB disease.
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Scriba, T.J., Nemes, E. Protection against tuberculosis by mucosal BCG administration. Nat Med 25, 199–201 (2019). https://doi.org/10.1038/s41591-019-0347-0