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Twenty-five ways clinical trials have changed in the last 25 years

Nature Medicinevolume 25pages25 (2019) | Download Citation

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Exploring the evolution, from analysis and endpoints to registration and regulations

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Change history

  • 04 April 2019

    The published online date in the HTML version of this article was originally 07 January 2018. The article was actually published online on 07 January 2019. The date has been updated.

References

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    Kaitin, K. I. Rising protocol complexity is hindering study performance, cost, and efficiency (Tufts CSDD Impact Report July/August) (Tufts Center for the Study of Drug Development, 2018).

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    da Costa, B. R. & Juni, P. Eur. Heart J. 35, 3336–3345 (2014).

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    Greco, T., Zangrillo, A., Biondi-Zoccai, G. & Landoni, G. Heart Lung Vessel 5, 219–225 (2013).

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    Wasserstein, R. L. & Lazar, N. A. Am. Stat. 70, 129–133 (2016).

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  1. Mike May is a freelance writer and editor based near, Houston, Texas, USA

    • Mike May

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Correspondence to Mike May.

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https://doi.org/10.1038/s41591-018-0314-1

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