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An exercise-induced messenger boosts memory in Alzheimer’s disease

An exercise-linked hormone, FNDC5/irisin, mediates the benefit of exercise in Alzheimer’s disease models by enhancing synaptic plasticity and memory.

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Fig. 1: Exercise-induced FNDC5/irisin prevents decline in cognitive function.


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Correspondence to Li Gan.

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Competing interests

L.G is a cofounder of Aeton Therapeutics, Inc.

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Chen, X., Gan, L. An exercise-induced messenger boosts memory in Alzheimer’s disease. Nat Med 25, 20–21 (2019).

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