Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News Feature
  • Published:

Calculated risk

Genetics and electronic health records come together to identify heritable traits

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout


  1. Tatonetti, N. P. et al. Clin. Pharmacol. Ther. 90, 133–142 (2011).

    Article  CAS  Google Scholar 

  2. Hsiao, C. J., Hing, E. & Ashman, J. Trends in electronic health record system use among office-based physicians: United States, 2007–2012 (National Health Statistics Reports, no. 75) 1–18 (National Center for Health Statistics, 2014).

  3. Kulynych, K. & Greely, H. T. J. Law Biosci. 4, 94–132 (2017).

    PubMed  PubMed Central  Google Scholar 

  4. Abul-Husn, N. S. et al. Science 354, aaf7000 (2016).

    Article  Google Scholar 

  5. Polubriaginof, F. C. G. et al. Cell 173, 1692–1704 (2018).

    Article  CAS  Google Scholar 

  6. Bastarache, L. et al. Science 359, 1233–1239 (2018).

    Article  CAS  Google Scholar 

  7. Hoffman, T. J. et al. Nat. Genet. 50, 401–413 (2018).

    Article  Google Scholar 

  8. Oni-Orisan, A. et al. Circulation: Genomic and Precision Medicine 11, e002043 (2018).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Shraddha Chakradhar.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chakradhar, S. Calculated risk. Nat Med 25, 6–8 (2019).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing