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DISEASE GENETICS

Linking brain tumors and epileptic seizures

Nature Medicinevolume 24pages16381639 (2018) | Download Citation

Mutationally activated BRAF-V600E influences the behavior of different types of cells in the brain and leads to promotion of seizures as well as brain tumors, indicating how both can be pharmacologically targeted in the clinic.

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Author information

Affiliations

  1. Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children’s Hospital Colorado and University of Colorado, Denver, CO, USA

    • Jean M. Mulcahy Levy
  2. Huntsman Cancer Institute and Department of Dermatology, University of Utah, Salt Lake City, UT, USA

    • Martin McMahon

Authors

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Competing interests

The authors declare no competing interests.

Corresponding authors

Correspondence to Jean M. Mulcahy Levy or Martin McMahon.

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https://doi.org/10.1038/s41591-018-0249-6

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