Fig. 6: Systematic profiling of oncRNAs in the extracellular compartment. | Nature Medicine

Fig. 6: Systematic profiling of oncRNAs in the extracellular compartment.

From: Cancer cells exploit an orphan RNA to drive metastatic progression

Fig. 6

a, smRNA-seq of RNA collected from conditioned medium from breast cancer cell lines and normal HMECs. Conditioned medium from each cell line was prepared in biologically independent duplicates, data from which were combined prior to c.p.m. calculations. The heat map shows the detection of oncRNAs in the extracellular compartment. T3p is indicated with an arrow. b, The detection of oncRNAs in serum samples collected from breast cancer patients with stage II and III disease32. As a point of reference, we have also included data from 35 healthy individuals from two independent studies (green: 11 samples from the exRNA atlas30; blue: 24 samples from a previous study31). T3p is indicated with an arrow.