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EPIGENETICS

Preconception cold–induced epigenetic inheritance

Nature Medicinevolume 24pages13081309 (2018) | Download Citation

Preconception cold–induced alterations of sperm DNA methylation result in offspring with altered brown adipose tissue and improved adaptation to overnutrition and hypothermia.

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Acknowledgements

I thank H. Johnson for assistance in preparation of this manuscript. This work was supported by grants from the National Institutes of Health (NIH; ES012974) and the John Templeton Foundation (50183) to M.K.S.

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Affiliations

  1. Center for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA, USA

    • Michael K. Skinner

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The author declares no competing interests.

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Correspondence to Michael K. Skinner.

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DOI

https://doi.org/10.1038/s41591-018-0187-3

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