CELL THERAPIES

Wound, heal thyself

An in vivo cellular reprogramming strategy to generate epithelial cells from wound mesenchymal cells promotes healing and provides a new avenue for the treatment of nonhealing wounds.

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Fig. 1: Skin healing can be achieved by cell reprogramming.

References

  1. 1.

    Eming, S. A., Martin, P. & Tomic-Canic, M. Sci. Transl. Med. 6, 265sr6 (2014).

    Article  Google Scholar 

  2. 2.

    Järbrink, K. et al. Syst. Rev. 5, 152 (2016).

    Article  Google Scholar 

  3. 3.

    Kurita, M. et al. Nature https://doi.org/10.1038/s41586-018-0477-4 (2018).

  4. 4.

    Zhao, R., Liang, H., Clarke, E., Jackson, C. & Xue, M. Int. J. Mol. Sci. 17, 2085 (2016).

    Article  Google Scholar 

  5. 5.

    Keyes, B. E. et al. Cell 167, 1323–1338.e14 (2016).

    CAS  Article  Google Scholar 

  6. 6.

    Lincoln, K. & Hyde, J. Wounds 28, 347–353 (2016).

    PubMed  Google Scholar 

  7. 7.

    Gurdon, J. B., Elsdale, T. R. & Fischberg, M. Nature 182, 64–65 (1958).

    CAS  Article  Google Scholar 

  8. 8.

    Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).

    CAS  Article  Google Scholar 

  9. 9.

    Ieda, M. et al. Cell 142, 375–386 (2010).

    CAS  Article  Google Scholar 

  10. 10.

    Srivastava, D. & DeWitt, N. Cell 166, 1386–1396 (2016).

    CAS  Article  Google Scholar 

Download references

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Correspondence to Shruti Naik.

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Naik, S. Wound, heal thyself. Nat Med 24, 1311–1312 (2018). https://doi.org/10.1038/s41591-018-0179-3

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