Targeting senescent cells with repurposed FDA-approved drugs improves phenotypes of aging in mice.
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Acknowledgements
M.S. was funded by the Institute for Research in Biomedicine (IRB–Barcelona), by the “la Caixa” Foundation, by grants from the Spanish Ministry of Economy (cofunded by the European Regional Development Fund) and by the European Research Council (from the European Union’s Horizon 2020 research and innovation programme). The IRB–Barcelona is recipient of a Severo Ochoa Award of Excellence from the Spanish Ministry of Economy. N.B. is the recipient of grants from the National Institutes of Health (P01AG021654), the Nathan Shock Center of Excellence for the Biology of Aging (P30AG038072) and the Glenn Center for the Biology of Human Aging (Paul Glenn Foundation for Medical Research). Funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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M.S. is the founder and a shareholder of Senolytic Therapeutics, Inc. (United States) and Senolytic Therapeutics, S.L. (Spain). N.B. is the founder of CohBar Inc. and a medical advisor to Life Biosciences.
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Serrano, M., Barzilai, N. Targeting senescence. Nat Med 24, 1092–1094 (2018). https://doi.org/10.1038/s41591-018-0141-4
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DOI: https://doi.org/10.1038/s41591-018-0141-4
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