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Intersection of schizophrenia genetics and placental complications

Genetic risk scores in schizophrenia are influenced by pregnancy complications that compromise the placenta, enhancing association of genes involved in metabolism and cellular stress with schizophrenia risk.

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Fig. 1: PRSs and pregnancy complications impacting the placenta intersect to increase the risk of schizophrenia diagnosis.


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Correspondence to Margaret M. McCarthy.

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McCarthy, M.M. Intersection of schizophrenia genetics and placental complications. Nat Med 24, 707–708 (2018).

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