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Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates

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Author information

Affiliations

  1. Sol Sherry Thrombosis Research Center, Temple University Medical School, Philadelphia, PA, USA

    • Weidong Xiao
  2. Department of Microbiology and Immunology, Temple University Medical School, Philadelphia, PA, USA

    • Weidong Xiao
  3. Cardiovascular Research Center, Temple University Medical School, Philadelphia, PA, USA

    • Weidong Xiao
  4. Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA, USA

    • Guangping Gao
  5. Division of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL, USA

    • Chen Ling
    •  & Roland W. Herzog
  6. Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    • Xiao Xiao
  7. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China

    • Xiao Xiao
  8. Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    • Richard J. Samulski

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Competing interests

The authors declare no competing interests.

Corresponding authors

Correspondence to Weidong Xiao or Guangping Gao or Chen Ling or Roland W. Herzog or Xiao Xiao or Richard J. Samulski.

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DOI

https://doi.org/10.1038/s41591-018-0062-2

Further reading

  • Wang et al. reply

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    Nature Medicine (2018)

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