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The promise and reality of new immune profiling technologies

This Comment discusses the explosion in innovative systems biology approaches in infectious disease studies. We outline the numerous challenges associated with these technologies from standardizing data science approaches to reproducibility of findings, as well as cost.

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Fig. 1: Evolution of multi-omic immune profiling techniques.

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Acknowledgements

T.J.H. receives grant support from the PolyBio Foundation and US National Institutes of Health/National Institute of Allergy and Infectious Disease (NIH/NIAID) K24AI145806. S.S. receives grant support from NIH/NIAID R01AI175614 and the San Francisco Chan Zuckerberg Biohub.

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Correspondence to Sara Suliman or Timothy J. Henrich.

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T.J.H. has received grant support from Merck.

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Suliman, S., Maison, D.P. & Henrich, T.J. The promise and reality of new immune profiling technologies. Nat Immunol 25, 1765–1769 (2024). https://doi.org/10.1038/s41590-024-01948-0

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