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COVID-19

Candida makes a lasting impression in COVID-19

Nature Immunology volume 24, pages 1782–1784 (2023)Cite this article

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Severe COVID-19 is marked by excessive inflammation that can persist after infection. The commensal yeast Candida albicans is now implicated in the acute and chronic immunopathology of COVID-19.

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Fig. 1: COVID-19 severity and recovery correlate with changes to the gut mycobiome and systemic markers of inflammation.

References

  1. Thaweethai, T. et al. JAMA 329, 1934–1946 (2023).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Kusakabe, T. Nat. Immunol. https://doi.org/10.1038/s41590-023-01637-4 (2023).

    Article  PubMed  Google Scholar 

  3. Iliev, I. D. & Leonardi, I. Nat. Rev. Immunol. 17, 635–646 (2017).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Gold, J. A. W. et al. Emerg. Infect. Dis. 29, 1433–1437 (2023).

    Article  PubMed Central  PubMed  Google Scholar 

  5. Kaul, A. et al. Inflamm. Bowel Dis. 18, 1872–1884 (2012).

    Article  PubMed  Google Scholar 

  6. Jukic, A., Bakiri, L., Wagner, E. F., Tilg, H. & Adolph, T. E. Gut 70, 1978–1988 (2021).

    Article  CAS  PubMed  Google Scholar 

  7. Ebinger, J. E. et al. PLoS One 15, e0236240 (2020).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  8. Shao, T. Y. et al. Cell Host Microbe 25, 404–417.e406 (2019).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  9. Yeung, F. et al. Cell Host Microbe 27, 809–822.e806 (2020).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  10. George, P. M. et al. Sci. Transl. Med. 14, eabo5795 (2022). A.

    Article  CAS  PubMed  Google Scholar 

  11. WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group. JAMA 326, 499–518 (2021).

    Article  Google Scholar 

  12. Lamers, M. M. et al. Science 369, 50–54 (2020).

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA

    Katherine Lagree & Peter Chen

  2. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

    Katherine Lagree

  3. The Karsh Division of Gastroenterology and Hepatology, Department of Medicine Cedars-Sinai Medical Center, Los Angeles, CA, USA

    Katherine Lagree

  4. Department of Medicine, Women’s Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

    Peter Chen

Authors
  1. Katherine Lagree
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  2. Peter Chen
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Correspondence to Peter Chen.

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The authors have no conflicts of interest.

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Lagree, K., Chen, P. Candida makes a lasting impression in COVID-19. Nat Immunol 24, 1782–1784 (2023). https://doi.org/10.1038/s41590-023-01648-1

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