A recent study identified a microglia–T cell communication axis that retains CD8+ T cells in brains with amyloid pathology. Data from this study indicate that CD8+ T cells restrict Alzheimer’s disease pathogenesis.
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The authors declare no competing interests.
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Reagin, K.L., Funk, K.E. CD8+ T cells pump the brakes on Alzheimer’s disease. Nat Immunol 24, 1597–1598 (2023). https://doi.org/10.1038/s41590-023-01622-x