Expression of the inhibitory receptor PD-1 on regulatory T cells in the tumor microenvironment provides intrinsic stabilization, proliferation and metabolic rewiring signals to restrain tumor immunity.
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Lee, JM., Sage, P.T. Check(point) yourself before you wreck yourself in tumors. Nat Immunol 24, 10–11 (2023). https://doi.org/10.1038/s41590-022-01391-z
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DOI: https://doi.org/10.1038/s41590-022-01391-z