Chronic viral infections can trigger ineffective antibody responses. A new study shows that deletion of B cell-specific Moloney murine leukemia virus integration site 1 (BMI-1) from B cells restores protective antibodies during chronic infection.
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Ripperger, T.J., Bhattacharya, D. Less BMI-1 is more for chronic infections. Nat Immunol 23, 6–8 (2022). https://doi.org/10.1038/s41590-021-01092-z
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DOI: https://doi.org/10.1038/s41590-021-01092-z
