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TFH CELLS

Selenium saves ferroptotic TFH cells to fortify the germinal center

Nature Immunology volume 22, pages 1074–1076 (2021)Cite this article

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Inhibition of ferroptosis via selenium supplementation promotes the survival of follicular helper T cells, boosting the germinal center and antibody response following vaccination in mice and people.

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Fig. 1: Selenium supplementation boosts TFH cells in mice and humans.

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Authors and Affiliations

  1. Immunology Programme, Babraham Institute, Cambridge, UK

    Michelle A. Linterman

  2. Department of Immunology and Inflammation, Imperial College London, London, UK

    Alice E. Denton

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  1. Michelle A. Linterman
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  2. Alice E. Denton
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Correspondence to Michelle A. Linterman.

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Linterman, M.A., Denton, A.E. Selenium saves ferroptotic TFH cells to fortify the germinal center. Nat Immunol 22, 1074–1076 (2021). https://doi.org/10.1038/s41590-021-01007-y

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