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Targeting resident macrophages in cancer

Nature Immunology volume 22, pages 1078–1079 (2021)Cite this article

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Tissue-resident alveolar macrophages promote early tumor invasiveness and induction of immunosuppressive regulatory T cells in non-small cell lung carcinoma.

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Fig. 1: TAM diversity and AM function in lung tumors in human and mouse.

References

  1. Casanova-Acebes, M. et al. Nature https://doi.org/10.1038/s41586-021-03651-8 (2021).

  2. Gibbings, S. L. et al. Am. J. Respir. Cell Mol. Biol. 57, 66–76 (2017).

    Article  CAS  Google Scholar 

  3. Schyns, J. et al. Nat. Commun. 10, 3964 (2019).

    Article  Google Scholar 

  4. Chakarov, S. et al. Science 363, eaau0964 (2019).

    Article  CAS  Google Scholar 

  5. Ural, B. B. et al. Sci. Immunol. 5, eaax8756 (2020).

    Article  CAS  Google Scholar 

  6. Loyher, P.-L. et al. J. Exp. Med. 215, 2536–2553 (2018).

    Article  CAS  Google Scholar 

  7. Zhu, Y. et al. Immunity 47, 323–338.e6 (2017).

    Article  CAS  Google Scholar 

  8. Reyfman, P. A. et al. Am. J. Respir. Crit. Care Med. 199, 1517–1536 (2019).

    Article  CAS  Google Scholar 

  9. Grant, R. A. et al. Nature 590, 635–641 (2021).

    Article  CAS  Google Scholar 

  10. Mould, K. J. et al. Am. J. Respir. Crit. Care Med. 203, 946–956 (2021).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Microbiology and Immunology, Dartmouth College, Hanover, NH, USA

    Xin Li, Kavita Rawat & Claudia V. Jakubzick

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  1. Xin Li
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  2. Kavita Rawat
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  3. Claudia V. Jakubzick
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Correspondence to Claudia V. Jakubzick.

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The authors declare no competing interests.

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Li, X., Rawat, K. & Jakubzick, C.V. Targeting resident macrophages in cancer. Nat Immunol 22, 1078–1079 (2021). https://doi.org/10.1038/s41590-021-01002-3

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