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NEUTROPHILS

Neutrophil life in three acts: a production by different stage directors

Analysis of the transcriptional landscape of inflammatory neutrophils discloses specific transcription factor engagement at the bone marrow–to-blood and the blood-to-tissue transitions.

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Fig. 1: Neutrophils remodel their transcriptional landscape at the BM–blood and blood–tissue transitions.

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Correspondence to Raphael Chevre or Oliver Soehnlein.

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R.C. declares no competing interests. O.S. receives funding from Novo Nordisk to study the potential of chronopharmacology for the treatment of atherosclerosis; he is also inventor on patents dealing with chemokine signaling and histones in inflammation.

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Chevre, R., Soehnlein, O. Neutrophil life in three acts: a production by different stage directors. Nat Immunol 22, 1072–1074 (2021). https://doi.org/10.1038/s41590-021-00997-z

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