Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

ASTHMA & ALLERGY

A soluble allergen sensor sounds the alarm

The identification of the acute phase protein serum amyloid A as a soluble allergen sensor sheds new light on the mechanisms involved in the induction of type II airway inflammation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Induction of type II inflammation by various HDM-derived allergens.

References

  1. Hammad, H. & Lambrecht, B. N. Immunity 43, 29–40 (2015).

    Article  CAS  PubMed  Google Scholar 

  2. Smole, U. et al. Nat. Immunol. https://doi.org/10.1038/s41590-020-0698-1 (2020).

  3. Jacquet, A. Trends Mol. Med. 17, 604–611 (2011).

    Article  CAS  PubMed  Google Scholar 

  4. Willart, M. A. et al. J. Exp. Med. 209, 1505–1517 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Smole, U., Kratzer, B. & Pickl, W. F. Eur. J. Immunol. 50, 624–642 (2020).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Espinassous, Q. et al. J. Immunol. 183, 1446–1455 (2009).

    Article  CAS  PubMed  Google Scholar 

  7. Bozinovski, S. et al. Proc. Natl Acad. Sci. USA 109, 935–940 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Li, L. et al. J. Leukoc. Biol. 99, 425–435 (2016).

    Article  CAS  PubMed  Google Scholar 

  9. Chen, K. et al. J. Immunol. 184, 3331–3335 (2010).

    Article  CAS  PubMed  Google Scholar 

  10. Vieira Braga, F. A. et al. Nat. Med. 25, 1153–1163 (2019).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rudi W. Hendriks.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hendriks, R.W. A soluble allergen sensor sounds the alarm. Nat Immunol 21, 724–726 (2020). https://doi.org/10.1038/s41590-020-0709-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41590-020-0709-2

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing