How should we talk about metabolism?

Immunologists used to avoid metabolism, but that is no longer possible. Now that we must talk about it, how can we do so in a way that enhances and clarifies our understanding of the role metabolism plays in the immune response?

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Fig. 1: Metabolic interconnections.


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Work in the laboratory of M.P.M. is supported by a grant from the UK Medical Research Council (MC_UU_00015/5) and by a Wellcome Trust Investigator award (110159/Z/15/Z). Work in the laboratory of L.A.O. is supported by the Wellcome Trust.

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Correspondence to Michael P. Murphy or Luke A. J. O’Neill.

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The authors declare no competing interests.

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Murphy, M.P., O’Neill, L.A.J. How should we talk about metabolism?. Nat Immunol 21, 713–715 (2020).

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