Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Sensing the gut microbiota

Paola Ricciardi-Castagnoli describes how her groups’ focus on mucosal immunity led to the discovery of how dendritic cells sense the gut microbiota to maintain homeostasis.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. Nussenzweig, M. C. & Steinman, R. M. J. Exp. Med. 151, 1196–1212 (1980).

    Article  CAS  Google Scholar 

  2. Janeway, C. A. Jr. Cold Spring Harb. Symp. Quant. Biol. 54, 1–13 (1989).

    Article  CAS  Google Scholar 

  3. Winzler, C. et al. J. Exp. Med. 185, 317–328 (1997).

    Article  CAS  Google Scholar 

  4. Poltorak, A. et al. Science 282, 2085–2088 (1998).

    Article  CAS  Google Scholar 

  5. Poltorak, A., Ricciardi-Castagnoli, P., Citterio, S. & Beutler, B. Proc. Natl Acad. Sci. USA 97, 2163–2167 (2000).

    Article  CAS  Google Scholar 

  6. Ricciardi-Castagnoli, P. & Granucci, F. Nat. Rev. Immunol. 2, 881–888 (2002).

    Article  CAS  Google Scholar 

  7. Granucci, F. et al. Nat. Immunol. 2, 882–888 (2001).

    Article  CAS  Google Scholar 

  8. Granucci, F., Zanoni, I., Feau, S. & Ricciardi-Castagnoli, P. EMBO J. 22, 2546–2551 (2003).

    Article  CAS  Google Scholar 

  9. Zanoni, I. et al. Nature 460, 264–268 (2009).

    Article  CAS  Google Scholar 

  10. Fric, J. et al. Blood 120, 1380–1389 (2012).

    Article  CAS  Google Scholar 

  11. Yu, H. B. et al. Nucleic Acids Res. 43, 836–847 (2015).

    Article  CAS  Google Scholar 

  12. Rescigno, M. et al. Nat. Immunol. 2, 361–367 (2001).

    Article  CAS  Google Scholar 

  13. Farache, J. et al. Immunity. 38, 581–595 (2013).

    Article  CAS  Google Scholar 

  14. Fric, J., Zelante, T. & Ricciardi-Castagnoli, P. Front. Immunol. 4, 513 (2014).

    Article  Google Scholar 

  15. Zelante, T. et al. Cell Rep. 12, 1789–1801 (2015).

    Article  CAS  Google Scholar 

  16. Mencarelli, A. et al. Nat. Commun. 9, 1102 (2018).

    Article  Google Scholar 

  17. Wu, H., Peisley, A., Graef, I. A. & Crabtree, G. R. Trends Cell Biol. 17, 251–260 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Paola Ricciardi-Castagnoli.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Ricciardi-Castagnoli, P. Sensing the gut microbiota. Nat Immunol 21, 704–705 (2020). https://doi.org/10.1038/s41590-020-0645-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41590-020-0645-1

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing