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MR1-RESTRICTED T CELLS

‘Bohemian Rhapsody’ of MR1T cells

A T cell recognizing the MHC class I–related molecule MR1, expressed by a wide range of cancer cell types, might have great potential for adoptive cell therapy in cancer.

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Fig. 1: Broad tumor recognition by MR1T cells.

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Correspondence to Lucia Mori.

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The University of Basel has filed a patent on MR1T cells.

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Mori, L., De Libero, G. ‘Bohemian Rhapsody’ of MR1T cells. Nat Immunol 21, 108–110 (2020). https://doi.org/10.1038/s41590-019-0588-6

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