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ANTIBODY THERAPY

One hits (almost) all

Nature Immunology volume 20, pages 1095–1097 (2019)Cite this article

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Therapeutic efficacy in inflammatory diseases is hampered by disease complexity. A monoclonal antibody that neutralizes IL-1R3, the common co-receptor of most inflammatory IL-1 cytokines, opens up new perspectives in effective disease management.

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Fig. 1: Multiple IL-1 cytokines involved in inflammatory diseases act through IL-1R3.

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Authors and Affiliations

  1. National Research Council, Naples, Italy

    Diana Boraschi

  2. Ben-Gurion University of the Negev, Beer-Sheva, Israel

    Ron N. Apte

  3. University of Giessen, Giessen, Germany

    Michael U. Martin

Authors
  1. Diana Boraschi
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  2. Ron N. Apte
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  3. Michael U. Martin
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Corresponding authors

Correspondence to Diana Boraschi, Ron N. Apte or Michael U. Martin.

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The authors declare no competing interests.

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Boraschi, D., Apte, R.N. & Martin, M.U. One hits (almost) all. Nat Immunol 20, 1095–1097 (2019). https://doi.org/10.1038/s41590-019-0463-5

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