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DEEP PROFILING

Elucidating the molecular circuitry of autoimmunity

Novel single-cell profiling technologies have delineated the cellular and molecular landscapes that dominate the joints in rheumatoid arthritis and the skin and kidneys in systemic lupus erythematosus, shedding light on potential pathogenic mechanisms.

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Fig. 1: Harnessing the power of single-cell profiling to study end-organ inflammation.

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Correspondence to Navin Varadarajan or Chandra Mohan.

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The authors declare no competing interests.

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Varadarajan, N., Mohan, C. Elucidating the molecular circuitry of autoimmunity. Nat Immunol 20, 777–778 (2019). https://doi.org/10.1038/s41590-019-0436-8

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