Supplementary Figure 5: Related to Figure 6. Induction of ILC1 memory is MCMV specific and cannot be formed by other viruses. | Nature Immunology

Supplementary Figure 5: Related to Figure 6. Induction of ILC1 memory is MCMV specific and cannot be formed by other viruses.

From: Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12

Supplementary Figure 5

WT mice were injected initially with either PBS or Influenza-PR8 intranasally (i.n.). 28 days PI, mice were subsequently challenged with either MCMV (i.n.) or Sendai virus (Sev) and analyzed 48 hours PI. (a) Quantification of intracellular IFN-y staining by percentage and MFI of ILC1 at 48 hours following primary and secondary MCMV challenge in i.v. CD45 unlabeled fraction of the lung. (b) Quantification of intracellular IFN-y staining by percentage and MFI of ILC1 at 48 hours following primary and secondary SeV challenge in i.v. CD45 unlabeled fraction of the lung. Data are representative of 3 independent experiments with (a) n=4 mice and (b) n=3 per group. Data are presented as the mean ± SEM.

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