Supplementary Figure 2: Expressions of immune-regulating proteins in peripheral blood Treg cell subpopulations and intratumoral Treg cells. | Nature Immunology

Supplementary Figure 2: Expressions of immune-regulating proteins in peripheral blood Treg cell subpopulations and intratumoral Treg cells.

From: Connecting blood and intratumoral Treg cell activity in predicting future relapse in breast cancer

Supplementary Figure 2

The percentages of CD73+ (n=40) (a), PD1+ (n=40), ****p<0.0001 (b), Tim3+ (n=40), ****p<0.0001 (c), LAG3+ (n=40), ****p<0.0001; ***p=0.0002 (d), GITR+ (n=20), ****p<0.0001; **p=0.007 (e) or HLA-DR+ (n=40), ****p<0.0001; ***p=0.0003 (f) in peripheral Tconv, Treg I, II and III cells from newly diagnosed patients with BC were determined by flow cytometry. Friedman test. Shown are mean ± s.e.m. Representative flow plots showing the percentages of LAG3+ (d), GITR+ (e), or HLA-DR+ (f) in intratumor Treg cells from untreated primary breast tumors (n=8). Data from intratumoral Treg cells were highlighted with purple box.

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