Members of the SLAM family of receptors promote the progression of invariant natural killer T cells through the thymic maturation process and facilitate proper host responses to exogenous lipid antigen through the recruitment and activity of SAP–Fyn and SHP-1, respectively.
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References
Griewank, K. et al. Immunity 27, 751–762 (2007).
Chen, S. et al. J. Exp. Med. 214, 475–489 (2017).
Detre, C., Keszei, M., Romero, X., Tsokos, G. C. & Terhorst, C. Semin. Immunopathol. 32, 157–171 (2010).
Lu, Y. et al. Nat. Immunol. https://doi.org/10.1038/s41590-019-0334-0 (2019).
Engel, P., Eck, M. J. & Terhorst, C. Nat. Rev. Immunol. 3, 813–821 (2003).
Veillette, A. Immunol. Rev. 214, 22–34 (2006).
Detre, Cynthia et al. Semin. Immunopathol. 32, 157–171 (2010).
Wang, H. & Hogquist, K. A. Front. Immunol. 9, 1450 (2018).
Cannons, J. L., Tangye, S. G. & Schwartzberg, P. L. Annu. Rev. Immunol. 29, 665–705 (2011).
Moran, A. E. et al. J. Exp. Med. 208, 1279–1289 (2011).
Nunez-Cruz, S. et al. J. Immunol. 181, 2311–2320 (2008).
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Iyer, S.S., Huang, YH. & Blumberg, R.S. SLAM-ing the brakes on iNKT cell selection. Nat Immunol 20, 378–379 (2019). https://doi.org/10.1038/s41590-019-0355-8
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DOI: https://doi.org/10.1038/s41590-019-0355-8
