Arginine methylation is a post-translational modification that controls the abundance of γc cytokine receptor on mature T cells by a post-transcriptional mechanism.
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Waickman, A. T., Park, J. Y. & Park, J. H. Cell. Mol. Life Sci. 73, 253–269 (2016).
Inoue, M. et al. Nat. Immunol. https://doi.org/10.1038/s41590-018-0222-z (2018).
Blanc, R. S. & Richard, S. Mol. Cell 65, 8–24 (2017).
Geoghegan, V., Guo, A., Trudgian, D., Thomas, B. & Acuto, O. Nat. Commun. 6, 6758 (2015).
Liu, F. et al. J. Clin. Invest. 125, 3532–3544 (2015).
Tee, W. W. et al. Genes Dev. 24, 2772–2777 (2010).
Bendelac, A., Savage, P. B. & Teyton, L. Annu. Rev. Immunol. 25, 297–336 (2007).
Bezzi, M. et al. Genes Dev. 27, 1903–1916 (2013).
Friesen, W. J., Massenet, S., Paushkin, S., Wyce, A. & Dreyfuss, G. Mol. Cell 7, 1111–1117 (2001).
Hong, C. et al. Immunity 40, 910–923 (2014).
Markiewicz, S. et al. J. Biol. Chem. 271, 14849–14855 (1996).
McCaughtry, T. M. et al. J. Exp. Med. 209, 2263–2276 (2012).
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Park, JY., Park, JH. Remote control of γc expression by arginine methylation. Nat Immunol 19, 1152–1154 (2018). https://doi.org/10.1038/s41590-018-0240-x
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