Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

HUMAN INFLUENZA

Influenza’s signature move

Nature Immunology volume 19, pages 518–520 (2018)Cite this article

Subjects

Analysis of whole-blood transcriptional profiles in adults hospitalized with influenza reveals time- and severity-related gene-expression signatures.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: The gene-expression pattern in influenza virus–infected patients reflects the severity of disease and time since infection.

References

  1. Iuliano, A.D. et al. Lancet 391, 1285–1300 (2018).

    Article  PubMed  Google Scholar 

  2. Rynda-Apple, A., Robinson, K. M. & Alcorn, J. F. Infect. Immun. 83, 3764–3770 (2015).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  3. Dunning, J. et al. Nat. Immunol. https://doi.org/10.1038/s41590-018-0111-5 (2018).

  4. Woods, C. W. et al. PLoS One 8, e52198 (2013).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Ramilo, O. et al. Blood 109, 2066–2077 (2007).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  6. Zaas, A. K. et al. Cell Host Microbe 6, 207–217 (2009).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  7. Chaussabel, D. et al. Immunity 29, 150–164 (2008).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  8. Schliehe, C. et al. Nat. Immunol. 16, 67 (2014).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Epigenetics Discovery Performance Unit, Oncology and Immunoinflammation Therapy Area Units, GSK Medicines Research Centre, Stevenage, UK

    David F. Tough

Authors
  1. David F. Tough
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to David F. Tough.

Ethics declarations

Competing interests

D.F.T. is an employee and shareholder of GlaxoSmithKline, which is involved in the research and development of medicines for the treatment of human disease.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tough, D.F. Influenza’s signature move. Nat Immunol 19, 518–520 (2018). https://doi.org/10.1038/s41590-018-0115-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41590-018-0115-1

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research