The activating natural killer cell receptor NKG2C can specifically recognize peptides derived from the cytomegalovirus protein UL40 in the context of HLA-E. This drives the expansion of a population of adaptive NKG2C+ natural killer cells.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Watzl, C. Adv. Immunol. 124, 137–170 (2014).
Hammer, Q. et al. Nat. Immunol. https://doi.org/10.1038/s41590-018-0082-6 (2018).
Halenius, A., Gerke, C. & Hengel, H. Cell. Mol. Immunol. 12, 139–153 (2015).
Cerwenka, A. & Lanier, L. L. Nat. Rev. Immunol. 16, 112–123 (2016).
Smith, H. R. et al. Proc. Natl Acad. Sci. USA 99, 8826–8831 (2002)..
Arase, H., Mocarski, E. S., Campbell, A. E., Hill, A. B. & Lanier, L. L. Science 296, 1323–1326 (2002).
Guma, M. et al. Blood 104, 3664–3671 (2004).
Schlums, H. et al. Immunity 42, 443–456 (2015).
Lee, J. et al. Immunity 42, 431–442 (2015).
Bjorkstrom, N. K. et al. J. Exp. Med. 208, 13–21 (2011).
Della Chiesa, M. et al. J. Immunol. 192, 1471–1479 (2014).
Koch, J., Steinle, A., Watzl, C. & Mandelboim, O. Trends Immunol. 34, 182–191 (2013).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing interests.
Rights and permissions
About this article
Cite this article
Watzl, C. Adaptive responses of innate lymphocytes. Nat Immunol 19, 426–427 (2018). https://doi.org/10.1038/s41590-018-0088-0
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41590-018-0088-0
