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IL-33 meets allergens at the gate

IL-33 is a mediator of allergic inflammation and is localized in mucosal tissues to respond rapidly to environmental insults. These include allergens themselves, which can directly activate IL-33 through their intrinsic proteolytic activity.

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Author information

Affiliations

  1. Insight BioConsulting, Bainbridge Island, WA, USA

    • Dirk E. Smith

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Competing interests

The author declares no competing interests.

Corresponding author

Correspondence to Dirk E. Smith.