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Histone modifications

Coaching LSD1 to ignore acetylation

Nature Chemical Biology (2024)Cite this article

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Engineered demethylase LSD1 opens a new avenue in developing tools to study intricate relationships between histone post-translational modifications that can be enzymatically edited.

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Fig. 1: Crosstalk between histone epigenetic marks.

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Authors and Affiliations

  1. Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO, USA

    Joshua C. Black & Tatiana G. Kutateladze

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  1. Joshua C. Black
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  2. Tatiana G. Kutateladze
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Correspondence to Tatiana G. Kutateladze.

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The authors declare no competing interests.

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Black, J.C., Kutateladze, T.G. Coaching LSD1 to ignore acetylation. Nat Chem Biol (2024). https://doi.org/10.1038/s41589-024-01710-5

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