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Mining microbial metabolism

Comamonas testosteroni utilizes aromatic compounds such as monomers from lignin and plastics, but the underlying metabolic pathways were elusive. Multi-omics analysis now clarifies the multifaceted regulation of its metabolism, facilitating strain engineering to convert substrates from lignin and plastics into valuable bioproducts.

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Fig. 1: Understanding the valorization of products derived from lignin and plastics by C. testosteroni.


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Correspondence to Yinjie J. Tang or Tae Seok Moon.

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Tang, Y.J., Moon, T.S. Mining microbial metabolism. Nat Chem Biol (2023).

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