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Mis-annotation of TnpB: case of TaRGET-ABE

An Author Correction to this article was published on 16 February 2023

The Original Article was published on 01 August 2022

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Fig. 1: Genomic architectures of IS200/IS605 MGEs and CRISPR-Cas12f systems.


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Authors and Affiliations



T.K. performed the sequence analysis. T.K. and V.S. wrote the manuscript.

Corresponding authors

Correspondence to Tautvydas Karvelis or Virginijus Siksnys.

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Competing interests

T.K. and V.S. are co-inventors on a patent application (PCT/IB2021/055958) filed by Vilnius University. V.S. is a chairman of and has financial interest in CasZyme.

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Nature Chemical Biology thanks the anonymous reviewers for their contribution to the peer review of this work.

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Karvelis, T., Siksnys, V. Mis-annotation of TnpB: case of TaRGET-ABE. Nat Chem Biol 19, 261–262 (2023).

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