Modern drug discovery relies upon intelligent exploration of ‘in stock’ and ‘on demand’ virtual libraries of compounds. A comparative analysis highlights the explosive expansion of accessible chemical space and also reveals challenges and opportunities arising for computational drug discovery.
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Cherkasov, A. The ‘Big Bang’ of the chemical universe. Nat Chem Biol 19, 667–668 (2023). https://doi.org/10.1038/s41589-022-01233-x
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DOI: https://doi.org/10.1038/s41589-022-01233-x
