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Glycobiology

A sweet feast

High-mannose N-glycans are common post-translational modifications that occur on many proteins. The mechanism by which these high-mannose N-glycans are consumed by species of Bifidobacterium has now been characterized, which is important given their positive role in human gut microbiota and their abundance in breastfed infants.

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Fig. 1: Comparison of how B. longum degrades high-mannose N-glycans.

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Correspondence to Lucy I. Crouch.

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Crouch, L.I. A sweet feast. Nat Chem Biol 19, 131–132 (2023). https://doi.org/10.1038/s41589-022-01199-w

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