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PRECISION ONCOLOGY

Drivers of intrinsic resistance

Precision oncology requires an understanding of the genes and pathways that dictate therapeutic response. Through specialized analysis of drug sensitivity patterns across hundreds of genomically annotated cancer cell lines, specific and actionable drivers of intrinsic resistance have been identified.

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Fig. 1: Discovery of actionable genes driving intrinsic resistance.

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Correspondence to Kris C. Wood.

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The author declares no competing financial interest.

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Wood, K.C. Drivers of intrinsic resistance. Nat Chem Biol 18, 579–581 (2022). https://doi.org/10.1038/s41589-022-00980-1

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