An approach based on enrichment of 5′ hydroxylated RNAs reveals a new self-cleaving ribozyme that maps to a very long non-protein-coding RNA in simians. The ribozyme is active only among hominin sequences, suggesting a recent acquisition of the activity.
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Chen, C.C., Lupták, A. Hunting for human ribozymes. Nat Chem Biol 17, 507–508 (2021). https://doi.org/10.1038/s41589-021-00778-7
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DOI: https://doi.org/10.1038/s41589-021-00778-7
