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CHROMATIN BIOLOGY

Oncohistones: corruption at the core

High-throughput biochemical and biological analyses of disease-associated histone mutations reveal key residues in globular cores that affect chromatin remodeling, nucleosome stability, and stem cell pluripotency.

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Fig. 1: Globular domain oncohistone mutations and the cellular processes they affect.

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Correspondence to Brian D. Strahl.

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Jain, K., Strahl, B.D. Oncohistones: corruption at the core. Nat Chem Biol 17, 370–371 (2021). https://doi.org/10.1038/s41589-021-00764-z

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