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Cell death

STACKing the odds for discoveries

Characterization of cell death kinetics identifies new on- and off-target small-molecule modulators of ferroptosis and reveals a role of amino acid metabolism in regulating ferroptosis sensitivity.

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Fig. 1: STACK reveals on- and off-target modulators of ferroptosis.

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Correspondence to Kıvanç Birsoy.

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Soula, M., Birsoy, K. STACKing the odds for discoveries. Nat Chem Biol 17, 627–628 (2021). https://doi.org/10.1038/s41589-021-00743-4

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